We have four distinctly different front page layouts:

Featured Stories - We list the top stories of your first section here.  This gets your users to the content right away.  We generally see more time in app and better ad performance with this design.
Tiles - We show all tiles in a consistent grid.  We display the image and title of the first story in the feed.  If your feed doesn't have images, make sure to supply one when you are entering your feeds in the admin.
Highlighter - This is a variation of the tile design.  We feature the first section by making it larger to draw the user to your most important section.
Power Strip - Every tile in this section is large and spans the width of the device.

Please note the slight design changes in our layout as it responds to larger tablet devices:

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